What is the purpose of a reference sample in DNA analysis?

What is the purpose of a reference sample in DNA analysis?

• A. To compare and verify the DNA profile derived from evidence with a known reference
• B. To store unused reagents
• C. To calibrate the camera
• D. To dispose of after use

Answer: (A)

The purpose is to provide a known DNA profile against which the DNA found on evidence can be compared. This comparison confirms whether the evidence DNA originates from the person of interest and helps exclude others, while also helping detect potential contamination or mixed profiles. The other options don’t fit because reference samples aren’t used for storing reagents, calibrating a camera, or disposing of materials.

The purpose is to provide a known DNA profile against which the DNA found on evidence can be compared. This comparison confirms whether the evidence DNA originates from the person of interest and helps exclude others, while also helping detect potential contamination or mixed profiles. The other options don’t fit because reference samples aren’t used for storing reagents, calibrating a camera, or disposing of materials.